Head of Intellectual Property

Manifold Biotechnologies

Manifold Biotechnologies

Administration
Boston, MA, USA
Posted on Sep 24, 2025

Manifold Bio is a dynamic biotech company building a pipeline of targeted biologics using a novel in vivo-centric discovery approach. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics. Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.

Position

We are seeking a Head of Intellectual Property to lead all aspects of our IP strategy and execution. This individual will partner closely with R&D, business development, and executive leadership to build a robust global IP portfolio that secures our platform technologies and therapeutic pipeline while positioning the company for long-term success.

Responsibilities

  • IP Strategy & Leadership
    • Define and implement a comprehensive global IP strategy aligned with corporate objectives.
    • Advise senior leadership on IP risks, opportunities, and competitive positioning.
  • Portfolio Development & Management
    • Direct all patent drafting, filing, prosecution, and portfolio management activities.
    • Collaborate with inventors and external counsel to generate and protect high-value IP.
    • Build a balanced portfolio covering platforms, therapeutic programs, and proprietary methods.
  • Collaboration & Enablement
    • Partner with R&D teams to identify inventions early and secure protection.
    • Train scientific staff on IP awareness and best practices.
    • Support business development with IP due diligence for partnerships, licensing, and M&A.
  • Risk Mitigation
    • Conduct freedom-to-operate analyses and monitor third-party IP.
    • Provide competitive IP landscaping to guide research and strategy.
    • Oversee IP enforcement, opposition, and litigation as needed.

Requirements

  • JD, PhD, or advanced degree in life sciences, biotechnology, or related field.
  • 10+ years of IP experience, with significant time in biotech/biopharma.
  • Demonstrated expertise in patent law, prosecution, and global IP landscapes.
  • Proven track record of building and managing IP portfolios that support business growth.
  • Strong communication skills, with the ability to clearly explain IP strategy to technical and non-technical stakeholders.
  • Prior leadership experience in-house at a biotech or biopharma company strongly preferred.

This Role Might Be Perfect For You If:

You are curious, passionate about science, and ready to act with scientific boldness and innovation. This role requires exceptional organization, quality and attention to detail, coupled with a commitment to meet or beat critical deadlines. You should be a team player who is also proactive and resourceful. with excellent written and verbal communication.

If you’re excited to use unique protein technologies to shape an innovative drug development strategy, build meaningful industry partnerships, and contribute directly to our mission of advancing breakthrough treatments, please apply!

We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.