Business Operations Associate
BigHat Biosciences
Sales & Business Development, Operations
San Mateo, CA, USA
USD 110k-130k / year
Posted on Feb 13, 2026
The Business Operations Associate will play a central role in enabling the day-to-day operations of BigHat’s headquarters and driving to execution across corporate functions. This role is ideal for a highly adaptable, detail-oriented professional who thrives in a fast-moving environment and enjoys flexing across a wide range of operational workstreams—including facilities, finance support, legal and compliance coordination, IT, procurement, and employee experience.
This individual will serve as a connective tissue across teams, helping translate business needs into action, proactively identifying gaps, and ensuring the company’s operational foundations can deliver.
- Application Deadline
- February 22, 2026
- Department
- Corporate Development & Operations
- Employment Type
- Full Time
- Location
- San Mateo, CA
- Workplace type
- Onsite
- Compensation
- $110,000 - $130,000 / year
Key Responsibilities
The Business Operations Associate will support multiple corporate workstreams, with responsibilities flexing based on business needs and priorities. Key areas of focus include:
Onsite & Workplace Operations
- Drive operation of BigHat’s San Mateo office, partnering with internal teams and external vendors to maintain a safe, functional, and engaging workplace.
- Coordinate site logistics, access, and general office needs in collaboration with lab operations and building management.
Cross-Functional Business Operations
- Partner with leaders across Operations, Finance, Legal, HR, IT, and other functions to support operational execution, special projects, and process improvements.
- Help document, improve, and scale internal workflows, tools, and information management practices.
- Act as a reliable “utility player,” stepping into new workstreams as priorities evolve.
Procurement, Vendors & Financial Operations
- Support purchasing, vendor coordination, and accounts payable processes in partnership with Finance and Accounting.
- Help ensure accurate tracking, documentation, and compliance across operational spend.
Employee Experience & Internal Enablement
- Support employee onboarding logistics, onsite experience, and internal events.
- Contribute to a positive and inclusive workplace culture through thoughtful operational execution.
IT, Systems & Administrative Support
- Coordinate with internal IT resources and external vendors to support hardware, systems access, and office technology needs.
- Assist with maintaining operational documentation and system records, as appropriate.
This role is expected to evolve over time, with opportunities to take on increasing ownership as the company grows.
Skills, Knowledge and Expertise
- 3+ years of experience in business operations, office or lab management, or a similar generalist role in a fast-paced environment (startup or biotech experience a plus).
- Strong organizational and execution skills, with the ability to manage multiple priorities across different functional areas.
- Proactive and clear communicator with a collaborative and service-oriented mindset.
- Sound judgment, discretion, and comfort working with sensitive or confidential information.
Preferred Attributes
- Energized by wearing many hats and passion for creating an engaging and inclusive workplace experience.
- Able to dive deep in a particular subject while balancing a wide set of responsibilities
- Reliable, resourceful, and hands-on approach to problem-solving.
- Interest in growing with the role and expanding operational scope over time.
About BigHat Biosciences
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.
Our Hiring Process
Stage 1:
Applied
Stage 2:
First screen
Stage 3:
Review
Stage 4:
Interviews
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